I've heard fantastic things about CouchDB.
Yeah, it's been getting hyped up a lot. It is pretty awesome that you can just PUT JSON there and that's all you need. If you like what you hear about CouchDB, you should check CouchApp thing. It basically app/ideology that if you store views and documents in the database already, why not the whole app. I'm not sure how well it actually works but demos/videos make it look pretty cool. With CouchDB my only worry is security because it's so "young".
You might want to read about how
BBC uses CouchDB - "We’ll probably get to 4 billion CouchDB requests tomorrow, 5 March 2010. Not bad for 32 CouchDB nodes running since last summer.".